SC.912.L.16.4

Students will reflect on prior knowledge, record their understanding of DNA replication based on a 3D computer model, and will then create a model demonstrating the process of DNA replication. Students will investigate where DNA replication occurs in the human body and why it occurs there. Additionally, students will investigate DNA mutations and their potential impact on the organism. Finally, students will summarize what they learned by collaborating with other classmates.

Type: Lesson Plan

This informational text resource is intended to support reading in the content area. In this lesson, students will analyze a text that addresses the issue of evolution by natural selection and mutation, using Florida "beach mice" as a case study. The lesson plan includes text-dependent questions, a writing prompt, answer keys, and a writing rubric. Ideas for extending the lesson are also included.

Type: Lesson Plan

This lesson about genetics and mutations investigates how red nosed reindeer could be raised in a livestock setting. Students will draw Punnett squares and design livestock plans for reproduction of red nosed reindeer.

Type: Lesson Plan

Students will explore the process of protein synthesis, specifically transcription and translation, using a sequenced graphic organizer and an interactive simulation (Lesson 1 & 2).

This resource contains 3 lessons:

• Lesson 1: Transcription & Translation
• Lesson 2: Lac Operon
• Lesson 3: Proteins & Cancer
  
  

As an extension (Lesson 3) the students will justify the applications of biotechnology that uses transcription and translation to synthesize proteins that target cancer cells or reason the possibilities of the amplification of antibodies using immortal cells.

They will explore how mutations, genetic or epigenetic (lifestyle-chemicals, radiation, viruses), resulting in cancer.

The student will connect changes that occur in the genetic code, during transcription and translation, to the deleterious impact on proto oncogenes that promote cell division and tumor suppressor genes that normally inhibit it.

Type: Lesson Plan

In this lesson, students will learn the effect of DNA mutations on protein formation and phenotype. The students will convert a DNA sequence to an amino acid sequence and use color-by-number pictures to show the difference between an original and mutated sequence. Through comparisons with other students in the class, the students will learn that not all mutations will result in a change, while some may cause a great deal of change in a gene (and therefore the protein and/or phenotype).

Type: Lesson Plan

"Transcription and Translation Made Easy" is an interactive whole-class activity that follows the transfer of information from the DNA to protein formation. The activity uses letters as parts of words as an analogy for amino acids as parts of proteins to allow the students to observe the type of mutations that may occur and the level of damage that each can cause.

Type: Lesson Plan

Part 1 - Students will transcribe and translate their way through a fun classroom scavenger hunt.
Part 2 - After genetically manipulating Joe's DNA, students try to develop the next Super Hero.

Type: Lesson Plan

Dive into genetic mutations and learn how they can alter the phenotypes of organisms.

Type: Original Student Tutorial

In the lab "From Gene to Protein - Transcription and Translation," students learn how genes are involved in the process of protein synthesis, including exploring specific examples such as albinism and sickle cell anemia. Students use paper models to simulate the process of transcription and translation.

Type: Teaching Idea

This informational text resource is intended to support reading in the content area. The text describes how natural selection occurs when mutations occur in an individual's DNA sequence. Two different populations can have two different genetic mutations yet end up with a similar phenotype.

Type: Text Resource

This informational text resource is intended to support reading in the content area. The text describes a rare form of dwarfism called Laron's Syndrome, which is associated with an unusually low incidence of cancer and diabetes. This combination of characteristics allows scientists to speculate on the relationship between all three conditions. It appears that a mutation that causes dwarfism protects against the common diseases of cancer and diabetes.

Type: Text Resource

This tutorial uses animation and practice opportunities to explore how mutations in DNA can impact the expression of a gene. Get a close up view of the nucleus of a fertilized egg and observe how mutations in different locations of a DNA strand influence the traits that are expressed during development.

Type: Tutorial

• Interviews with expert scientists about the genome and mutant organisms
• Examples on model organisms used in genome research
• Animation explaining how mutations occur

Type: Video/Audio/Animation