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Students will reflect on prior knowledge, record their understanding of DNA replication based on a 3D computer model, and will then create a model demonstrating the process of DNA replication. Students will investigate where DNA replication occurs in the human body and why it occurs there. Additionally, students will investigate DNA mutations and their potential impact on the organism. Finally, students will summarize what they learned by collaborating with other classmates.

Type: Lesson Plan

Students will explore the process of protein synthesis, specifically transcription and translation, using a sequenced graphic organizer and an interactive simulation (Lesson 1 & 2).

This resource contains 3 lessons:

• Lesson 1: Transcription & Translation
• Lesson 2: Lac Operon
• Lesson 3: Proteins & Cancer
  
  

As an extension (Lesson 3) the students will justify the applications of biotechnology that uses transcription and translation to synthesize proteins that target cancer cells or reason the possibilities of the amplification of antibodies using immortal cells.

They will explore how mutations, genetic or epigenetic (lifestyle-chemicals, radiation, viruses), resulting in cancer.

The student will connect changes that occur in the genetic code, during transcription and translation, to the deleterious impact on proto oncogenes that promote cell division and tumor suppressor genes that normally inhibit it.

Type: Lesson Plan

In this lesson, students learn about DNA, the building block of genetic material. Students learn the basic components of DNA and see how they fit together. The teacher will offer activities and support to support with these goals. The goal of this lesson is to familiarize students to the cell and its DNA as the genetic material that manages how the cell will function. It is recommended to teach this lesson before teaching heredity is the passage of these instructions from one generation to another.

Type: Lesson Plan

How is it that all cells in our body have the same genes, yet cells in different tissues express different genes? A basic notion in biology that most high school students fail to conceptualize is the fact that all cells in the animal or human body contain the same DNA, yet different cells in different tissues express, on the one hand, a set of common genes, and on the other, express another set of genes that vary depending on the type of tissue and the stage of development. In this video lesson, the student will be reminded that genes in a cell/tissue are expressed when certain conditions in the nucleus are met. Interestingly, the system utilized by the cell to ensure tissue specific gene expression is rather simple. Among other factors - all discussed fully in the lesson - the cells make use of a tiny scaffold known as the "Nuclear Matrix or Nucleo-Skeleton". This video lesson spans 20 minutes and provides 5 exercises for students to work out in groups and in consultation with their classroom teacher. The entire duration of the video demonstration and exercises should take about 45-50 minutes, or equivalent to one classroom session. There are no supplies needed for students' participation in the provided exercises. They will only need their notebooks and pens. However, the teacher may wish to emulate the demonstrations used in the video lesson by the presenter and in this case simple material can be used as those used in the video. These include play dough, pencils, rubber bands (to construct the nuclear matrix model), a tennis ball and 2-3 Meters worth of shoe laces. The students should be aware of basic information about DNA folding in the nucleus, DNA replication, gene transcription, translation and protein synthesis.

Type: Lesson Plan

Learn how DNA is copied and explain how this process allows cells to have identical genetic information with this interactive tutorial.

Type: Original Student Tutorial

Dr. David McNutt explains how large clonal plant populations can be analyzed with microsatellite analysis of their DNA.

Download the CPALMS Perspectives video student note taking guide.

Type: Perspectives Video: Expert

A discussion of the applications of Knot Theory, replication of DNA, enzymes, and fluid dynamics.

Type: Perspectives Video: Expert

This informational text resource is intended to support reading in the content area. This article provides some of the newest and most exciting information relating to the DNA in living things. It is a synopsis of a recent experiment in which scientists were able to successfully add two new "letters" into DNA and have the cell replicate these new bases. This could lead to advances in genetics, medicine, and various other fields of study.

Type: Text Resource

This Khan Academy video reviews the basic processes of DNA replication and protein synthesis. It then goes on to explain how the terms chromosome, chromatin, and chromatid, relate to each other.

Type: Tutorial

This Khan Academy video briefly describes DNA replication and then goes into a thorough explanation of both transcription and translation.

Type: Tutorial

Your body is made of cells -- but how does a single cell know to become part of your nose, instead of your toes? The answer is in your body's instruction book: DNA. Joe Hanson compares DNA to a detailed manual for building a person out of cells -- with 46 chapters (chromosomes) and hundreds of thousands of pages covering every part of you.

Type: Tutorial

This tutorial will help the learners to understand structure of DNA and how this structure allows for accurate replication.

Type: Tutorial

This tutorial will help learners understand the process of DNA replication, including the enzymes involved. Learners will be able to recognize that an exact copy of DNA must be created prior to cell division.

Type: Tutorial

DNA is the genetic material of all known living organisms and some viruses. DNA contains two stands wrapped around each other in a helix, and these stands are held in place by four chemicals called bases: adenine (A), guanine (G), cytosine (C), and thymine (T). The bases pair up with each other in a specific manner to form units called base pairs - adenine always pairs with thymine, and cytosine always pairs with guanine.
In this game your job is to first make exact copies of a double-stranded DNA molecule by correctly matching base pairs to each strand, and to then determine which organism the DNA belongs to.

Type: Virtual Manipulative

In this interactive game, the students will understand how a DNA molecule is built up, how the copies of the DNA molecule made and what is the meaning of base-pairing. The job of the students in this game is to first make exact copies of a double-stranded DNA molecule by correctly matching the base pairs to each strand, and to then determine which organism the DNA belongs to.

Type: Virtual Manipulative

This resource is an animation to explain DNA replication. It is an interactive simulation activity for students. See also "Transcription and Translation Animation" to get all of the steps from DNA to protein.

Type: Virtual Manipulative