SC.912.L.16.11

Discuss the technologies associated with forensic medicine and DNA identification, including restriction fragment length polymorphism (RFLP) analysis.
General Information
Subject Area: Science
Grade: 912
Body of Knowledge: Life Science
Idea: Level 3: Strategic Thinking & Complex Reasoning
Standard: Heredity and Reproduction -

A. DNA stores and transmits genetic information. Genes are sets of instructions encoded in the structure of DNA.

B. Genetic information is passed from generation to generation by DNA in all organisms and accounts for similarities in related individuals.

C. Manipulation of DNA in organisms has led to commercial production of biological molecules on a large scale and genetically modified organisms.

D. Reproduction is characteristic of living things and is essential for the survival of species.

Date Adopted or Revised: 02/08
Date of Last Rating: 05/08
Status: State Board Approved

Related Courses

This benchmark is part of these courses.
2000330: Biology 2 Honors (Specifically in versions: 2014 - 2015, 2015 - 2018, 2018 - 2022, 2022 and beyond (current))
2000430: Biology Technology (Specifically in versions: 2014 - 2015, 2015 - 2022, 2022 and beyond (current))
3027010: Biotechnology 1 (Specifically in versions: 2015 - 2022, 2022 and beyond (current))
3027020: Biotechnology 2 (Specifically in versions: 2015 and beyond (current))
2002480: Forensic Science 1 (Specifically in versions: 2014 - 2015, 2015 - 2017, 2017 - 2022, 2022 and beyond (current))
2002490: Forensic Sciences 2 (Specifically in versions: 2014 - 2015, 2015 - 2017, 2017 - 2022, 2022 and beyond (current))
2000440: Genetics Honors (Specifically in versions: 2014 - 2015, 2015 - 2022, 2022 and beyond (current))
2000520: Bioscience 3 Honors (Specifically in versions: 2014 - 2015, 2015 - 2022, 2022 - 2023 (current), 2023 and beyond)

Related Access Points

Alternate version of this benchmark for students with significant cognitive disabilities.

Related Resources

Vetted resources educators can use to teach the concepts and skills in this benchmark.

Lesson Plans

Using DNA to Identify People:

 Learning objectives:  Students will learn what DNA fingerprinting is, what it is used for, and how it is used in paternity testing and forensics.  Students will see how this technique actually works in lab.  Students will learn how to analyze the gels used in this technique to match babies to parents, and crime scene evidence to suspects.

Type: Lesson Plan

Life after Death: Some Genes Remain "Alive":

In this lesson, students will analyze an informational text intended to support reading in the content area. The article explains what happens to certain genes after an organism has died. This lesson also introduces a related video that explains how the fields of Genetics and Biotechnology have affected the field of Forensic Science. By reading the article and viewing the video, students will learn about new discoveries in gene function after death and the impact varying fields of science have upon another. This lesson includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric.

Type: Lesson Plan

How to be a Molecular Biologist the Easy Way:

This lesson plan details the ethical concepts of biotechnology and allows students to explore basic concepts of manipulating and analyzing DNA in a classroom setting. The lesson takes the students through a discussion of controversial topics related to molecular biology and biotechnology, DNA isolation, restriction digestion of DNA, gel electrophoresis, and DNA cloning.

Type: Lesson Plan

Personal DNA Testing:

A lesson with multi-media components from PBS/NOVA that focuses on DNA testing, including techniques, purposes, and considerations for biotechnology and human decisions regarding health. Students will learn about single nucleotide polymorphisms, how they are used in science, and how they are being used in the medical field. Students will apply this knowledge by looking at a mock data set and probabilities to inform medical recommendations.

Type: Lesson Plan

Original Student Tutorial

Assessment of Genetic Biodiversity through Biotechnology:

Examine how genetic identification is aiding marine biologists studying organisms in deep ocean regions. This interactive tutorial also features a CPALMS Perspectives video.

Type: Original Student Tutorial

Perspectives Video: Experts

Assessment of Genetic Biodiversity of Deep-sea Fish in the Gulf of Mexico:

Dr. Mahmood Shivji describes research efforts to assess biodiversity of fish species in the deep waters of the Gulf of Mexico through the use of genetic testing.

Download the CPALMS Perspectives video student note taking guide.

Type: Perspectives Video: Expert

DNA Microsatellite Analysis for Plant Ecology:

Dr. David McNutt explains how large clonal plant populations can be analyzed with microsatellite analysis of their DNA.

Download the CPALMS Perspectives video student note taking guide.

Type: Perspectives Video: Expert

Perspectives Video: Professional/Enthusiast

DNA Biotechnology and Forensic Science:

Watch as Sue Livingston reveals how DNA and forensic biotechnology methods can be used to help solve crimes.

Download the CPALMS Perspectives video student note taking guide.

Type: Perspectives Video: Professional/Enthusiast

Text Resource

Some Genes Remain "Alive" for Days After the Body Dies:

This informational text resource is intended to support reading in the content area. Researchers from the University of Washington, led by microbiologist Peter Nobel, found that hundreds of genes reawaken and function in mice and fish for up to four days. Nobel also discovered that these genes are responsible for responding to stress and regulating the immune system. There were also others that are important for a developing embryo being used and these shouldn’t be needed after birth. In addition, the genes may also be linked to increased cancer in organ transplants and scientists are hoping to use the information in forensic science to better estimate a time of death.

Type: Text Resource

Tutorials

DNA Sequencing Using the Sanger Method:

DNA sequencing is a technique for determining the complete sequence of bases (As, Ts, Gs, and Cs) for a particular piece of DNA. Sequencing is relatively time consuming, as the process must be done to fairly short lengths of DNA at a time. This tutorial will help you to understand the process of DNA sequencing.

Type: Tutorial

DNA Fingerprinting:

This tutorial will help you to visualize how DNA fingerprinting uses the pattern of DNA fragments caused by specific enzymes to identify individual organisms including humans, animals, plants or any other organism with DNA.

Type: Tutorial

Video/Audio/Animations

Lab: Restriction Analysis:

  • An interactive exercise for using agarose gel electrophoresis for separating DNA molecules
  • Explain how restriction endonucleases is used in restriction analysis of DNA

Type: Video/Audio/Animation

Lab: DNA Extraction:

  • Background on the discovery of the DNA double helix
  • Contains an interactive activity for base pairing
  • Contains an interactive activity for DNA extraction

Type: Video/Audio/Animation

Lab: DNA Fingerprint: Alu:

  • Background on tracking human ancestry using the alu marker
  • Animation on polymerase chain reaction, PCR
  • Interactive activity for performing PCR

Type: Video/Audio/Animation

Virtual Manipulatives

Gel electrophoresis Virtual Lab:

This virtual lab provides an excellent resource to show how biotechnology can be incorporated into an actual situation. The student will be walked through the gel electrophoresis process and then apply the results to solve a crime.

Type: Virtual Manipulative

DNA Extraction Virtual Lab:

In this interactive Biotechniques virtual lab, you will isolate DNA from a human test subject and learn the uses for DNA obtained through extraction. The "Try It Yourself" section below the virtual lab gives instruction and background information about how to extract DNA from living tissue using basic materials available in grocery stores.

Type: Virtual Manipulative

Original Student Tutorials Science - Grades 9-12

Assessment of Genetic Biodiversity through Biotechnology:

Examine how genetic identification is aiding marine biologists studying organisms in deep ocean regions. This interactive tutorial also features a CPALMS Perspectives video.

Student Resources

Vetted resources students can use to learn the concepts and skills in this benchmark.

Original Student Tutorial

Assessment of Genetic Biodiversity through Biotechnology:

Examine how genetic identification is aiding marine biologists studying organisms in deep ocean regions. This interactive tutorial also features a CPALMS Perspectives video.

Type: Original Student Tutorial

Lesson Plan

Using DNA to Identify People:

 Learning objectives:  Students will learn what DNA fingerprinting is, what it is used for, and how it is used in paternity testing and forensics.  Students will see how this technique actually works in lab.  Students will learn how to analyze the gels used in this technique to match babies to parents, and crime scene evidence to suspects.

Type: Lesson Plan

Tutorials

DNA Sequencing Using the Sanger Method:

DNA sequencing is a technique for determining the complete sequence of bases (As, Ts, Gs, and Cs) for a particular piece of DNA. Sequencing is relatively time consuming, as the process must be done to fairly short lengths of DNA at a time. This tutorial will help you to understand the process of DNA sequencing.

Type: Tutorial

DNA Fingerprinting:

This tutorial will help you to visualize how DNA fingerprinting uses the pattern of DNA fragments caused by specific enzymes to identify individual organisms including humans, animals, plants or any other organism with DNA.

Type: Tutorial

Video/Audio/Animations

Lab: Restriction Analysis:

  • An interactive exercise for using agarose gel electrophoresis for separating DNA molecules
  • Explain how restriction endonucleases is used in restriction analysis of DNA

Type: Video/Audio/Animation

Lab: DNA Extraction:

  • Background on the discovery of the DNA double helix
  • Contains an interactive activity for base pairing
  • Contains an interactive activity for DNA extraction

Type: Video/Audio/Animation

Lab: DNA Fingerprint: Alu:

  • Background on tracking human ancestry using the alu marker
  • Animation on polymerase chain reaction, PCR
  • Interactive activity for performing PCR

Type: Video/Audio/Animation

Virtual Manipulatives

Gel electrophoresis Virtual Lab:

This virtual lab provides an excellent resource to show how biotechnology can be incorporated into an actual situation. The student will be walked through the gel electrophoresis process and then apply the results to solve a crime.

Type: Virtual Manipulative

DNA Extraction Virtual Lab:

In this interactive Biotechniques virtual lab, you will isolate DNA from a human test subject and learn the uses for DNA obtained through extraction. The "Try It Yourself" section below the virtual lab gives instruction and background information about how to extract DNA from living tissue using basic materials available in grocery stores.

Type: Virtual Manipulative

Parent Resources

Vetted resources caregivers can use to help students learn the concepts and skills in this benchmark.