Standard #: SC.912.L.18.1


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Describe the basic molecular structures and primary functions of the four major categories of biological macromolecules.


General Information

Subject Area: Science
Grade: 912
Body of Knowledge: Life Science
Idea: Level 2: Basic Application of Skills & Concepts
Standard: Matter and Energy Transformations -

A. All living things are composed of four basic categories of macromolecules and share the same basic needs for life.

B. Living organisms acquire the energy they need for life processes through various metabolic pathways (primarily photosynthesis and cellular respiration).

C. Chemical reactions in living things follow basic rules of chemistry and are usually regulated by enzymes.

D. The unique chemical properties of carbon and water make life on Earth possible.

Date Adopted or Revised: 02/08
Date of Last Rating: 05/08
Status: State Board Approved
Assessed: Yes

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Related Access Points

Access Point Number Access Point Title
SC.912.L.18.In.1 Identify that carbohydrates, fats, proteins, and nucleic acids (macromolecules) are important for human organisms.
SC.912.L.18.Su.1 Recognize that humans use proteins, carbohydrates, and fats.
SC.912.L.18.Pa.1 Recognize that humans need different kinds of food.


Related Resources

Lesson Plans

Name Description
School Lunch Showdown

Students will apply their knowledge of the structure and function of macromolecules in order to rank four school lunch menus for the National School Lunch Program. Students will practice communicating persuasively and professionally with public officials by providing insight to their ranking process through use of a letter that cites evidence and justifies reasoning in this model eliciting activity.

Model Eliciting Activities, MEAs, are open-ended, interdisciplinary problem-solving activities that are meant to reveal students’ thinking about the concepts embedded in realistic situations. Click here to learn more about MEAs and how they can transform your classroom.

The Last Supper: Identifying Macromolecules

The students will solve a mystery using laboratory tests for different types of macromolecules. They will use argumentation to justify and communicate their claim. They will construct explanations and communicate with one another to determine which macromolecule would be best to eat in different scenarios. Students will be able to identify the structure and functions of the four main types of macromolecules. The students will use laboratory testing to determine the identity of an unknown. They will fill in a chart about the structures, functions, and examples for each macromolecule type and then they will practice their knowledge by answering short response questions relating the macromolecules to the real world. Finally, they will review using a whole-class cooperative activity and take a quiz about the structures and functions of macromolecules.

Macromolecules and the Athlete

Students will analyze an athlete's diet to better understand the macromolecules needed for survival. Students will learn the primary function and structure of carbohydrates, lipids, and proteins.

A Day of Macromolecules

The purpose of this lesson plan is to exercise students' knowledge of the structures and functions of the four major types of macromolecules by playing Macromolecular Go Fish, solving Macromolecular Math problems, and finally competing with one another in a macromolecule-style game of Names from a Hat.

Meet Your Macromolecules

This lesson teaches applied concepts associated with the four macromolecules: lipids, carbohydrates, proteins, and nucleic acids.

Protein Synthesis: Transcription & Translation

Students will explore the process of protein synthesis, specifically transcription and translation, using a sequenced graphic organizer and an interactive simulation (Lesson 1 & 2).

This resource contains 3 lessons:

  • Lesson 1: Transcription & Translation
  • Lesson 2: Lac Operon
  • Lesson 3: Proteins & Cancer

As an extension (Lesson 3) the students will justify the applications of biotechnology that uses transcription and translation to synthesize proteins that target cancer cells or reason the possibilities of the amplification of antibodies using immortal cells.

They will explore how mutations, genetic or epigenetic (lifestyle-chemicals, radiation, viruses), resulting in cancer.

The student will connect changes that occur in the genetic code, during transcription and translation, to the deleterious impact on proto oncogenes that promote cell division and tumor suppressor genes that normally inhibit it.

Organic Macromolecules

In this lesson students will be learning to recognize and compare and contrast the four different organic macromolecules. This lesson will require the viewing of a 7 minute video and will require 4 large groups of six students to work cooperatively together in a team effort to complete an organic macromolecule chart.

Macromolecule Snack Attack

In this MEA, students will be introduced to the four biological macromolecules through common snack foods found in vending machines. They will act as dietitians selecting and ranking snack foods based on given their nutrition labels and knowledge of the structure and function of the four biological macromolecules.

Model Eliciting Activities, MEAs, are open-ended, interdisciplinary problem-solving activities that are meant to reveal students’ thinking about the concepts embedded in realistic situations. Click here to learn more about MEAs and how they can transform your classroom.

A Macromolecule Mystery: Who Took Jerell's iPod?

Students use their knowledge of organic compounds to solve a simulated mystery (Who took Jerell's iPod) by testing for triglycerides, glucose, starch, and protein. This lab deepens student understanding of biological functions and food sources of various organic compounds.

Macromolecule Food Indicator Lab

In this lesson students will complete a lab using indicators to determine which foods contain carbohydrates, lipids, proteins, and/or starches. The lab includes pre-lab questions, discussion, lab experimentation, post lab questions, results and conclusion. The students will submit a completed lab report that will be graded based on a rubric.

Original Student Tutorials

Name Description
The Macromolecules of Life: Carbohydrates

Learn about the basic molecular structures and primary functions of carbohydrates with this interactive tutorial.

This is part 2 in a five-part series. Click below to explore other tutorials in the series.

The Macromolecules of Life: Lipids

Learn about the basic molecular structures and primary functions of lipids with this interactive tutorial.

This is part 3 in a five-part series. Click below to explore other tutorials in the series.

The Macromolecules of Life: Proteins

Learn about the basic molecular structures and primary functions of proteins with this interactive tutorial.

This is part 4 in a five-part series. Click below to explore other tutorials in the series.

The Macromolecules of Life: Nucleic Acids

Learn to identify and describe the structural and functional features of nucleic acids, one of the 4 primary macromolecule groups in biological systems, with this interactive tutorial.

This is Part 3 in 5-part series. Click below to open the other tutorials in the series:

The Macromolecules of Life: Overview

Learn to identify the four basic biological macromolecules (carbohydrates, lipids, proteins, and nucleic acids) by structure and function with this interactive tutorial.

This is part 1 in a five-part series. Click below to explore other tutorials in the series.

Perspectives Video: Professional/Enthusiasts

Name Description
Linseed Oil Properties for Oil Painting

Oil paints certainly left their mark on history and are widely used in art today! Produced with funding from the Florida Division of Cultural Affairs.

Download the CPALMS Perspectives video student note taking guide.

Oil Painting Technique

Understanding the science behind oil painting can help you become a better artist! Produced with funding from the Florida Division of Cultural Affairs.

Download the CPALMS Perspectives video student note taking guide.

Perspectives Video: Teaching Idea

Name Description
Macromolecule Matching

Learn about macromolecules with this tabletop exercise.

Download the CPALMS Perspectives video student note taking guide.

Resource Collection

Name Description
Online Macromolecular Museum

The Online Macromolecular Museum (OMM) is a site for the display and study of macromolecules. Macromolecular structures, as discovered by crystallographic or NMR methods, are scientific objects in much the same sense as fossil bones or dried specimens: they can be archived, studied, and displayed in aesthetically pleasing, educational exhibits. Hence, a museum seems an appropriate designation for the collection of displays that we are assembling. The OMM's exhibits are interactive tutorials on individual molecules in which hypertextual explanations of important biochemical features are linked to illustrative renderings of the molecule at hand.

Teaching Idea

Name Description
Murder and A Meal

In a "Murder Mystery" scenario, students will use their knowledge of the structure and properties of macromolecules to conduct a forensic investigation.

Tutorials

Name Description
DNA

This Khan Academy video describes the structure of the molecule DNA in great detail. It also discuses the role DNA plays in the process of protein synthesis, explaining transcription and translation. The video discusses the relationship between DNA and chromosomes as well.

The Chemical Structure of DNA


This tutorial will help the learners with their understanding of chemical structure of DNA.

Video/Audio/Animations

Name Description
Biological Molecules Paul Anderson describes the four major biological molecules found in living things. He begins with a brief discussion of polymerization. Dehydration synthesis is used to connect monomers into polymers and hydrolysis breaks them down again. The major characteristics of nucleic acids are described as well as there directionality from 3' to 5' end.
MIT BLOSSOMS - Methods for Protein Purification This Protein Purification video lesson is intended to give students some insight into the process and tools that scientists and engineers use to explore proteins. It is designed to extend the knowledge of students who are already somewhat sophisticated and who have a good understanding of basic biology. The question that motivates this lesson is, "what makes two cell types different?" and this question is posed in several ways. Such scientific reasoning raises the experimental question: how could you study just a subset of specialized proteins that distinguish one cell type from another? Two techniques useful in this regard are considered in the lesson. This video lesson will easily fit into a 50-minute class period, and prerequisites include a good understanding of cellular components (DNA vs. Protein vs. lipid) and some understanding of the physical features of proteins (charge, size etc). The simple cell model used here can be assembled in any kind of container and with any components of different solubility, density, charge etc. In-class activities during the video breaks include discussions, careful observations, and the use of a "very simple cell" model to explore two techniques of protein purification. Students and teachers can spend additional time discussing and exploring the question of "how we know what we know" since this lesson lends itself to the teaching of the process of science as well.
Photosynthesis animation and other cell processes in animation This site has fantastic short Flash animations of intricate cell processes, including photosynthesis and the electron transport chain.

Virtual Manipulative

Name Description
The Tree of Life's Macromolecules - The Concord Consortium A Java Program that allows the students to explore the macromolecules via closer looks at different organisms. After exploring the macromolecules there are questions they can answer about the individual macromolecules and summary questions. The students can also print a report of their answers for the teacher.

Student Resources

Original Student Tutorials

Name Description
The Macromolecules of Life: Carbohydrates:

Learn about the basic molecular structures and primary functions of carbohydrates with this interactive tutorial.

This is part 2 in a five-part series. Click below to explore other tutorials in the series.

The Macromolecules of Life: Lipids:

Learn about the basic molecular structures and primary functions of lipids with this interactive tutorial.

This is part 3 in a five-part series. Click below to explore other tutorials in the series.

The Macromolecules of Life: Proteins:

Learn about the basic molecular structures and primary functions of proteins with this interactive tutorial.

This is part 4 in a five-part series. Click below to explore other tutorials in the series.

The Macromolecules of Life: Nucleic Acids:

Learn to identify and describe the structural and functional features of nucleic acids, one of the 4 primary macromolecule groups in biological systems, with this interactive tutorial.

This is Part 3 in 5-part series. Click below to open the other tutorials in the series:

The Macromolecules of Life: Overview:

Learn to identify the four basic biological macromolecules (carbohydrates, lipids, proteins, and nucleic acids) by structure and function with this interactive tutorial.

This is part 1 in a five-part series. Click below to explore other tutorials in the series.

Tutorials

Name Description
DNA:

This Khan Academy video describes the structure of the molecule DNA in great detail. It also discuses the role DNA plays in the process of protein synthesis, explaining transcription and translation. The video discusses the relationship between DNA and chromosomes as well.

The Chemical Structure of DNA:


This tutorial will help the learners with their understanding of chemical structure of DNA.

Video/Audio/Animation

Name Description
Photosynthesis animation and other cell processes in animation: This site has fantastic short Flash animations of intricate cell processes, including photosynthesis and the electron transport chain.


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